Predictive value of standard serum markers for bone metastases in prostate cancer
نویسندگان
چکیده
Abstract Background The early detection of bone metastases is very important in prostate cancer follow-up. This study aimed to compare conventional tumor markers, namely free prostate-specific antigen (free PSA), total (total PSA/total PSA ratio, alkaline phosphatase (ALP) values, Gleason scores and 99 m Tc-MDP scintigraphy findings the prediction cancer. Methods In total, 175 patients with who underwent whole-body were included study. All selected scintigraphic studies reprocessed. Free PSA, values recorded. Results results our show that presence metastasis correlates weakly ratio (rho = 0.179), 0.318) score 0.382), moderately ALP 0.539), (0.416). Only variable had a diagnostic value cutoff was 76.50 IU/L, 80% sensitivity 82.1% specificity. Conclusion According study; not considered as reliable parameter cases follow-up for development. IU / L specificity predicting
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ژورنال
عنوان ژورنال: African Journal of Urology
سال: 2021
ISSN: ['2090-2379', '1110-5704', '1961-9987']
DOI: https://doi.org/10.1186/s12301-021-00170-w